Our Evidence

The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches.

A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study.

Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.

Validation of a host gene expression test for bacterial/viral discrimination in immunocompromised hosts.

Previously derived host gene expression classifiers identify bacterial and viral etiologies of acute febrile respiratory illness in a south Asian population.

Validation of a host response test to distinguish bacterial and viral respiratory infection.

Epithelial and airway secretion host response distinguishes bacterial and viral infections.

Host gene expression classifiers diagnose acute respiratory illness etiology.

Improved detection of bacterial and viral coinfection using host gene expression classification.

Unsupervised analysis of transcriptomics in bacterial sepsis across multiple datasets reveals three robust clusters.

A community approach to mortality prediction in sepsis via gene expression analysis.

A host-based RT-PCR gene expression signature to identify acute respiratory viral infection.

Performance of a host response gene expression classifier for detection of bacterial and viral infection in febrile children.

Host gene expression signatures for discriminating clinical outcomes of severe trauma: a multicenter study.

A community-based host gene expression analysis for diagnosis of respiratory viral vs. bacterial infection.

A genomic signature of influenza infection shows potential for presymptomatic detection, guiding early therapy, and monitoring clinical responses.

Transcriptomic analysis of the host response and innate resilience to Enterotoxigenic Escherichia coli infection in humans.

Potential cost-effectiveness of early identification of hospital-acquired infection in critically ill patients.

Broad range host response gene expression classifiers identify infecting organisms in humans.

Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.

A genomic signature to rapidly identify influenza and differentiate from other respiratory infections.

Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans.

Classification of acute respiratory viral infections by host gene expression signatures.