Transcriptomics
Your DNA doesn't change. Your gene expression does — every day.
Transcriptomics measures gene expression — the active, changing readout of which genes are turned on or off in your body right now. Unlike static genetic tests, transcriptomic markers respond in real time to medication, disease, stress, and lifestyle.
What Is Transcriptomics?
Every cell in your body contains the same DNA — the same 20,000+ protein-coding genes you were born with. But at any given moment, only a fraction of those genes are active. Transcriptomics measures which genes are turned on, how loudly they're expressed, and how those patterns change over time.
When a gene is activated, it produces messenger RNA (mRNA) — the molecular instructions that tell your cells what to build. By measuring mRNA levels, we get a real-time snapshot of your biology in action: which pathways are firing, which are suppressed, and how your body is responding to the world around it.
Genomics
Tells you what recipes are in the cookbook. Your DNA sequence — the full set of instructions, inherited and unchanging.
Transcriptomics
Tells you which recipes are being prepared right now. Your mRNA expression — dynamic, responsive, changing every day in response to medication, stress, diet, and disease.
Proteomics
Tells you what dishes are on the table. Protein levels — the functional output, but harder to measure and slower to change.
How Transcriptomic Testing Works
From sample to insight — a streamlined pipeline built on isothermal amplification and quantitative PCR — proven methods in molecular measurement.
Sample
Blood draw or swab. RNA is stabilized at the point of collection.
Extract
RNA is isolated using Biomeme's streamlined prep chemistry.
Amplify
RNA targets are reverse-transcribed, amplified, and measured in real-time.
Analyze
Expression levels are quantified and compared against reference baselines.
Report
Actionable insights delivered via cloud-connected dashboard.
Transcriptomics vs. Genomics vs. Proteomics
Three ways to read biology. Only one captures what's happening right now — with the technology Biomeme already has.
| Genomics | Transcriptomics | Proteomics | |
|---|---|---|---|
| Measures | DNA sequence | mRNA expression levels | Protein levels |
| Changes Over Time? | Mostly static | Yes — dynamic, real-time | Yes — but slower |
| What It Reveals | Genetic predisposition | Active gene regulation | Functional output |
| Testing Method | Sequencing / SNP arrays | Isothermal / qPCR / RNA-Seq | Mass spectrometry |
| At Point of Care? | Emerging | Biomeme's Core Competency | No — lab only |
Transcriptomics sits at the intersection of what's dynamic and what's measurable in real-time — making it uniquely suited to Biomeme's multiplexed platform.
What Can Transcriptomics Measure?
From immune response to therapeutic monitoring — gene expression reveals what blood chemistry and imaging can't.
Inflammatory Response
Cytokine gene expression (TNFA, IL1B, IL6) reveals the intensity and trajectory of inflammatory pathways — essential for monitoring therapeutic response.
Metabolic Activity
Lipogenesis, insulin signaling, and mitochondrial function — transcriptomic markers capture metabolic shifts days to weeks before they appear in standard blood panels.
Explore GLP-1 & Metabolic MonitoringDrug Response
Confirm that a therapeutic is engaging its molecular targets. Pharmacodynamic monitoring via gene expression — objective proof the drug is working, not just prescribed.
Immune Status
Distinguish bacterial from viral infections by reading the host immune signature — the foundation of our work in sepsis detection.
Explore Sepsis DiagnosticsTreatment Durability
Longitudinal expression monitoring detects molecular drift — when a treatment starts losing efficacy — before clinical symptoms appear. Early warning, molecular precision.
Environmental Stress
Gene expression signatures for biological exposure, toxin response, and environmental stress markers — critical for biodefense and public health surveillance.
Explore Exposure MonitoringMultiplexed Transcriptomics. Anywhere.
Biomeme is the only platform that can run multiplexed transcriptomic panels at the point of care. Our Biomeme/5 instrument measures up to 48 targets simultaneously — enough for comprehensive gene expression profiling in a single run.
Combined with our streamlined sample prep, cloud-connected software, and CLIA-certified laboratory (One Health Labs), we deliver a complete end-to-end transcriptomic testing solution — from sample to insight.
All running on
One Platform · One Instrument · One Lab
Transcriptomics In Action
From monitoring therapeutic response to distinguishing infection types — transcriptomics powers everything we do.
Wellness
Monitor molecular response to therapeutics, track metabolic health, and detect treatment drift — the next frontier in personalized wellness.
Explore WellnessHealthcare
Host response testing reads the body's own immune signature to distinguish bacterial from viral infections — enabling smarter prescribing decisions.
Explore Host ResponseResearch
Custom transcriptomic panels for environmental monitoring, agricultural pathogen detection, and field-deployable research applications.
Explore ResearchTranscriptomic Deep Dives
Explore how gene expression is revolutionizing specific fields of study.
GLP-1 Response
GLP-1 receptor agonists trigger massive, systemic shifts in gene expression. Discover why transcriptomics is the key to understanding responder plateaus and metabolic health.
Read the Deep DiveBiological Aging
DNA is chronological. Expression is biological. Learn how transcriptomics provides the ultimate molecular biomarker for cellular senescence and inflammaging.
Read the Deep DiveAthletic Performance
Wearables show physical output; gene expression shows molecular strain. Discover how transcriptomics predicts injury risk and monitors recovery.
Read the Deep DiveTrauma & Sepsis
Predict the crash before it happens. Learn how transcriptomics can detect the host's earliest transcriptional stress signatures — in some studies, 24–48 hours before clinical symptoms of sepsis appear.
Read the Deep DiveEnvironmental Exposure
Decoding the invisible threat. Learn how transcriptomics measures the active molecular footprint of toxic chemical and radiological exposure before chronic symptoms manifest.
Read the Deep DiveSee Transcriptomics In Action
From monitoring GLP-1 response to distinguishing bacterial infections — explore how Biomeme's platform puts transcriptomic insights where they're needed most.